The school has one of the best and beautifully designed science laboratories which consists of Physics, Chemistry and Biology labs. They are in turn equipped with all the modern apparatus and instruments.The school has a well-equipped and spacious physics/chemistry laboratory which can comfortably accommodate about 40 students at a time. All the major equipments necessary to conduct the required experiments, which form the part of the curriculum, are found in this lab.

The lab consists of all the required physical balances, meters, U-tube apparatus, meter bridges, rheostats,

chemicals, glass apparatus, test tubes, burettes, pipettes, volumetric flasks, beakers etc. to facilitate the students in their experiments. The lab is also equipped with sufficient apparatus to provide opportunity to the students for project work. Students at the senior level are also able to design electronic circuits in the lab as part of the activity.

The biology laboratory of Nirmala Rani High School is located on the first floor adjacent to the other labs. The cupboards are used to store chemicals, reagents and glass ware. This lab is also equipped with various types of microscopes, specimens, slides, models, charts, human skeleton and much more. This ensures that the students have all the necessary equipments to understand and work on the entire biology practical course. This lab is capable of conducting experiments for junior as well as senior classes. All kinds of biology project work can be undertaken in the laboratory.